What to Expect During TMS Therapy?
Transcranial Magnetic Stimulation therapy is a revolutionary treatment for various mental health disorders, It is FDA-approved for major depressive disorder and obsessive-compulsive disorder. TMS is a non-invasive procedure and has gained popularity for its effectiveness in treating treatment-resistant depressive symptoms. Clinical trials have proven the safety and efficacy of TMS Therapy in treating patients who’ve had an inadequate response to prior antidepressant medications.

Understanding TMS:
A Brief Overview
TMS works by delivering repeated magnetic pulses to the prefrontal cortex, the area of the brain involved in mood control. These pulses generate a small electric current in the targeted brain cells stimulating the nerve cells and improving symptoms of major depression and other mental health conditions. The efficacy of this approach has been demonstrated in numerous clinical trials, particularly for patients who haven’t responded well to traditional antidepressant medications.

Initial Consultation
- Review your medical history and current symptoms
- Discuss your previous treatments for depression or other mental health disorders
- Explain the TMS procedure in detail, including its proven efficacy in clinical trials
- Assess your suitability for TMS therapy, including potential contraindications to TMS
- Address any questions or concerns you may have
Your First TMS Treatment Session
- First, you will be seated in a comfortable chair and fitted with a hygiene cap and your head will be measured utilizing various scalp landmarks to locate the treatment site
- Next, the doctor will place a magnetic coil against your head and you will hear a clicking sound and feel a tapping sensation on your scalp.
- The doctor will then adjust the TMS Therapy system so that the device will give just enough energy to send electromagnetic pulses into the brain so that your hand twitches. In cases in which we are treating for OCD, the dose will be adjusted to give enough energy to send electromagnetic pulses into the brain so that the foot twitches. The amount of energy required to make the hand or foot twitch is called the “motor threshold”.
- Once motor threshold is determined, the magnetic coil will be moved to the treatment site, and you will receive the treatment as a series of pulses prescribed by the doctor.
- Total treatment time is between 3-45min depending on the settings your doctor prescribes.
Ongoing TMS Sessions
- Frequency and Duration: Most patients undergo daily TMS therapy 5 days a week, over a period of 4 to 6 weeks. Each session typically lasts about 3-45 minutes.
- Consistency: It's crucial to maintain a consistent treatment schedule for optimal results.
- Monitoring: Your progress will be continuously monitored throughout the treatment course. Your doctor may adjust the treatment parameters as needed.
What to Expect During TMS Treatment?
- Symptom Improvement: Some patients report improvement in their depression symptoms within the first few weeks, while others may take longer to notice changes.
- Side Effects: Common side effects include mild headache, scalp discomfort. These typically subside after the first week or two of treatment.
- Mood Fluctuations: It's normal to experience ups and downs in your mood during the treatment course. Keep your doctor informed of any significant changes.
Post-Treatment Care
- Follow-up Appointments: You'll have follow-up appointments to monitor your progress and discuss any ongoing symptoms.
- Maintenance Sessions: Some patients benefit from regular "booster" sessions to maintain improvement.
- Continued Mental Health Care: Your doctor may recommend ongoing therapy or medication management to complement the effects of and maintain the symptom improvements from TMS.
The TMS Journey: From Consultation to Completion

Beyond Depression: Other Applications of TMS
- Obsessive-Compulsive Disorder (OCD): TMS has been FDA-approved for treating OCD symptoms.
- Anxiety Disorders: Research is ongoing into the effectiveness of TMS for various anxiety disorders. TMS is FDA approved for anxious depression.
- Anxiety Disorders: Research is ongoing into the effectiveness of TMS for various anxiety disorders. TMS is FDA approved for anxious depression.
- Smoking Cessation: TMS if FDA approved for smoking cessation.
- Post-Traumatic Stress Disorder (PTSD): Some studies suggest TMS may help alleviate PTSD symptoms.
- Chronic Pain: TMS is being explored as a potential treatment for certain types of chronic pain.
The Science Behind TMS: How It Works
- Magnetic Fields: The TMS device generates magnetic fields similar in strength to those used in MRI machines.
- Neuroplasticity: Over time, TMS may promote neuroplasticity, helping to modulate and rewire brain circuits involved in depression and other mental health disorders.
- Neurotransmitter Release: This stimulation is believed to increase the release of neurotransmitters like serotonin, norepinephrine, and dopamine, which play crucial roles in mood regulation.
- Brain Stimulation: These magnetic fields pass through the skull and induce small electrical currents in the targeted brain cells.

TMS vs. Other Treatments:
A Comparison
TMS vs. Other Treatments: A Comparison
- Medication: Unlike antidepressants, TMS doesn't cause systemic side effects like weight gain or sexual dysfunction. Additionally, clinical trials have shown TMS to be effective for many patients who didn't respond adequately to antidepressant medications.
- Psychotherapy: TMS can be used alongside therapy for a comprehensive treatment approach.
- Electroconvulsive Therapy (ECT): TMS is less invasive than ECT and doesn't require anesthesia or sedation or cause memory loss.
- Deep Brain Stimulation Therapies: TMS is non-invasive and doesn't require surgery or implanted devices, unlike deep brain stimulators.

Is TMS Right for You?
- Individuals with treatment-resistant depression.
- Those who cannot tolerate antidepressant medications due to side effects.
- Patients looking for a non-invasive, drug-free treatment option.
- Individuals who've had inadequate responses to prior antidepressant medications, as proven effective in clinical trials.
- Presence of magnetic sensitive implants or devices in or near the head or within 12 inches of the coil that cannot be removed
- History of uncontrolled seizures or epilepsy
- Severe substance use disorders
- Presence of brain tumors or other neurological conditions
Embracing Hope
with TMS
Frequently asked questions about what to expect
What should I expect at the first TMS session?
Once cleared for TMS therapy, you will be scheduled for your first TMS session. The first TMS treatment session is typically used for mapping and positioning so later visits can focus on treatment.
Will I be awake during TMS?
Yes. Treatments are done in the office while you stay awake and alert. Understanding the mechanism behind TMS can help alleviate concerns and set realistic expectations.
Is TMS a long process?
Embarking on TMS therapy is a journey. A typical course is daily sessions over several weeks, with mapping at the start and follow-up with Dr. Peralta as you progress.
Where can I read more?
See what TMS therapy is and insurance and financing for coverage questions. The National Institute of Mental Health also outlines how brain stimulation therapies work.
